Endocrine Abstracts

Studies have demonstrated the presence of androgen receptors in osteoblasts and osteocytes, confirming that androgens are important for the maintenance of bone in men. Additionally to steroid hormones, histamine stimulates osteoclast differentiation and survival and plays a role in the inflammatory response via H2 receptors. We purposed to investigate whether cimetidine, an histamine H2 receptors antagonist and antiandrogenic drug, interferes in the periodontal tissue damages ...